ProteinMusic: Translating Life into Sound, Composing Proteins from Melody

Every protein has a hidden musical score — its amino acid sequence and 3D folded structure can be mapped onto chords, rhythms, and timbres. ProteinMusic is a two-way bridge: Protein to Music turns your sequences or PDB structures into customizable jazz compositions; Music to Protein decodes your MIDI, WAV or MP3 files into novel protein sequences with predicted 3D structures. Explore the boundary where molecular biology becomes audible — and music becomes tangible.

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Two-Way Translation:

  • Protein → Music: Input a DNA/RNA/protein sequence or PDB file. Each amino acid's physicochemical properties (hydrophobicity, polarity, structural complexity) are mapped to jazz chords; spatial neighbors shape melody timbre. Output: playable MIDI + MP3 with a 3-channel mixer (chords / bass / melody) you can customize before voting.
  • Music → Protein: Upload a MIDI, WAV, or MP3 file. Chord progressions are extracted and mapped back to amino acid sequences via species-specific codon frequency profiles. ESMFold then predicts the 3D structure, so you can literally compose a brand-new protein from your music.